Mapping the BKCa Channel's “Ca2+ Bowl”
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منابع مشابه
Mapping the BKCa Channel's “Ca2+ Bowl”
There is controversy over whether Ca(2+) binds to the BK(Ca) channel's intracellular domain or its integral-membrane domain and over whether or not mutations that reduce the channel's Ca(2+) sensitivity act at the point of Ca(2+) coordination. One region in the intracellular domain that has been implicated in Ca(2+) sensing is the "Ca(2+) bowl". This region contains many acidic residues, and la...
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ژورنال
عنوان ژورنال: Journal of General Physiology
سال: 2004
ISSN: 1540-7748,0022-1295
DOI: 10.1085/jgp.200409052